pentobarbital will lessen the extent or effect of alfuzosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
fentanyl iontophoretic transdermal system and pentobarbital both increase sedation. Keep away from or Use Alternate Drug. Limit use to individuals for whom alternative treatment solutions are insufficient
pentobarbital will minimize the level or effect of erlotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will reduce the extent or impact of phenytoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.
pentobarbital will minimize the extent or influence of fruquintinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. If coadministration with moderate CYP3A4 inducers is unavoidable, continue to administer fruquintinib at suggested dosage.
fentanyl transmucosal and pentobarbital both of those increase sedation. Avoid or Use Alternate Drug. Limit use to sufferers for whom choice remedy options are inadequate
pentobarbital will reduce the extent or impact of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lessen the level or impact of copyright topical by affecting hepatic enzyme CYP2B6 metabolism. Insignificant/Importance Unidentified.
pentobarbital will minimize the extent or result of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital and daridorexant each raise sedation. Modify Therapy/Keep track of Carefully. Coadministration increases threat of CNS despair, which can result in additive impairment of psychomotor effectiveness and trigger daytime impairment.
Contraindicated (1)pentobarbital will reduce the extent or outcome of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Warning when discontinuing CYP3A4 here inducers which might be coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may possibly boost and may end up in probably fatal respiratory depression.
Apply evidence-centered tips and complete expertise in pentobarbital's pharmacology, pharmacokinetics, and potential drug interactions for that Secure and helpful use of pentobarbital.
pentobarbital will lower the level or result of itraconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.